University Medical Center Utrecht
Professor den Ruijter's aim is to translate knowledge from experimental research to the patient. In women, the diagnosis of heart disease is a problem. Most available diagnostics for heart disease have been tested in men and directly translated to women. Nowadays we are increasingly becoming aware that male-derived tests do not always detect heart disease in women. There are interesting sex differences in the pathophysiology of heart disease that may explain why diagnostic tests developed in men fail to detect heart disease in women. Therefore, her goal is to obtain novel biomarkers that facilitate the diagnosis of heart disease in women, and to understand why these sex differences occur.